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Lung Nodule

What is a Pulmonary Nodule?

A pulmonary nodule is a small, round or oval-shaped concentrated mass or lesion located within the lung tissue. These formations are generally smaller than 3 cm and can be solitary (a single nodule) or multiple. Nodules can be benign (non-cancerous) or malignant (cancerous), and most are discovered incidentally during imaging studies performed for other reasons.

Pulmonary nodules can arise due to many different causes. Some nodules cause no symptoms, while others may be indicators of serious diseases. Therefore, accurate evaluation and follow-up are very important. Healme Clinic offers effective solutions with advanced technologies and an expert team for the diagnosis and monitoring of pulmonary nodules.

Causes of Pulmonary Nodules

Infections

Nodules can develop after past tuberculosis, fungal infections, or bacterial infections in the lungs. These types of nodules are usually calcified (hardened with calcium) and benign.

Inflammatory Diseases

Autoimmune diseases such as rheumatologic conditions or sarcoidosis can cause pulmonary nodules. In these cases, nodules are usually widespread and bilateral.

Benign Tumors

Benign lung tumors like hamartomas can appear as nodules. These nodules generally do not grow and can be monitored without surgery.

Malignant Tumors

Lung cancer or metastatic cancers spreading from other parts of the body to the lungs can appear as nodules. Malignant nodules usually have irregular borders, rapid growth, and certain imaging features.

Symptoms of Pulmonary Nodules

Nodules Without Symptoms

Most pulmonary nodules do not cause any symptoms and are detected incidentally during chest X-rays or computed tomography (CT) scans.

Symptoms When Present

If the nodule is large or if the underlying disease is malignant, the following symptoms may occur:

  • Chronic cough
  • Chest pain
  • Shortness of breath
  • Coughing up blood (hemoptysis)
  • Weight loss
  • Fatigue

These symptoms can overlap with other lung diseases, so differential diagnosis is required.

How is a Pulmonary Nodule Diagnosed?

Chest X-Ray

This is the initial imaging method but may be insufficient for detecting small nodules.

Computed Tomography (CT)

CT evaluates the size, shape, border characteristics, and calcification of the nodule. It is the most commonly used method for diagnosis.

PET-CT

Positron Emission Tomography (PET) measures the metabolic activity of the nodule and helps determine whether it is malignant. It is especially useful for evaluating suspicious nodules.

Biopsy

For a definitive diagnosis, a tissue sample can be taken and examined pathologically. This procedure can be performed via bronchoscopy or needle biopsy.

Blood Tests

Certain tumor markers and inflammation indicators can contribute to the evaluation.

How to Determine If a Nodule is Malignant?

Size

Nodules larger than 3 cm carry a higher risk of malignancy.

Border Characteristics

Nodules with smooth borders tend to be benign, whereas those with irregular or spiculated (spiky) borders are more likely malignant.

Growth Rate

Nodules that grow over time may be malignant. Therefore, nodules are followed up with imaging at regular intervals.

Calcification

Calcification usually indicates that the nodule is benign.

Density and FDG Uptake

Nodules that take up FDG on PET-CT are more likely to be malignant. Nodules with low uptake are usually benign.

Treatment of Pulmonary Nodules

Follow-Up

Small, low-risk nodules are monitored with regular imaging. Follow-up intervals vary between 3 to 12 months depending on risk status.

Surgical Intervention

Nodules with high malignancy risk or confirmed cancer via biopsy can be surgically removed. Healme Clinic offers safe and effective interventions with minimally invasive techniques (VATS, robotic surgery).

Radiofrequency Ablation

In some patients, local treatment methods can be applied instead of surgery. Radiofrequency ablation destroys the nodule using high heat.

Immunotherapy and Chemotherapy

For patients diagnosed with malignant nodules and detected spread, systemic treatments are planned. This process should be managed by a multidisciplinary team.

Healme Clinic’s Approach to Pulmonary Nodules

Healme Clinic provides services with advanced imaging technologies and experienced pulmonology and thoracic surgery specialists for the diagnosis and treatment of pulmonary nodules. Within a multidisciplinary approach, each patient is evaluated individually and a personalized treatment plan is created.

Services Offered at Healme Clinic

  • Early diagnosis with low-dose lung CT
  • Detailed evaluation with PET-CT
  • Targeted biopsy procedures
  • Minimally invasive surgical techniques
  • Oncology consultation and treatment planning
  • Periodic follow-up and patient education

How to Prevent Pulmonary Nodules?

Quitting Smoking

Smoking is the leading cause of lung cancer. Quitting smoking reduces the risk of nodule formation and malignancy.

Regular Check-Ups

Regular lung screening is recommended for high-risk groups (e.g., people over 50 years old with a long smoking history).

Avoiding Air Pollution

People living in industrial areas should avoid prolonged exposure to harmful airborne particles.

Healthy Nutrition and Exercise

Eating antioxidant-rich foods and exercising regularly helps strengthen the immune system.

Pulmonary nodules are mostly benign but can sometimes be the first sign of early-stage lung cancer. Therefore, when a nodule is detected, careful evaluation and necessary follow-up are critically important. Healme Clinic guides its patients through this process with scientific approaches, advanced technology, and an expert team.

Protect your respiratory health and get accurate information about pulmonary nodules by consulting Healme Clinic.