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Thymus Diseases

What Are Thymus Diseases?
The thymus is a small organ located in the upper front part of the chest cavity, just above the heart. As an important part of the immune system, the thymus is especially active during childhood and adolescence, where it facilitates the maturation of T cells. T cells are immune cells that protect the body against infections.

Thymus diseases refer to various conditions that affect the structure or function of this organ. These diseases include thymoma, thymic cyst, thymic hyperplasia, and thymus cancer. Although thymus diseases are rare, early diagnosis and treatment are important because some can impact the immune system and other organs.

Functions and Importance of the Thymus
The primary function of the thymus is the maturation of T lymphocytes and the regulation of the immune system. The thymus is very active in childhood but shrinks and decreases in function after puberty. Nevertheless, it continues to play an important role in maintaining healthy immune function throughout life.

Types of Thymus Diseases

Thymoma
Thymomas are benign or malignant tumors that develop in the thymus. They generally grow slowly, and symptoms often appear late. Thymomas are mostly seen between the ages of 40 and 60.

Symptoms include chest pain, shortness of breath, cough, and fatigue. Thymomas are sometimes associated with neuromuscular diseases such as myasthenia gravis.

Thymic Cysts
Thymic cysts are fluid-filled sacs that develop inside or around the thymus. They are usually benign and asymptomatic. However, large cysts can cause breathing difficulties or become infected.

Thymic Hyperplasia
Thymic hyperplasia is the enlargement of thymic tissue beyond normal. This condition is often observed in immune-related diseases, especially in patients with myasthenia gravis.

Thymus Cancer
Thymus cancer is a rare and aggressive disease. Unlike thymomas, it can grow rapidly and spread to surrounding tissues. Early diagnosis and surgical intervention are crucial.

Symptoms of Thymus Diseases
Thymus diseases often do not show symptoms in early stages. As the disease progresses, the following symptoms may appear:

  • Chest pain or pressure sensation
  • Shortness of breath or cough
  • Difficulty swallowing
  • Fatigue and weakness
  • Muscle weakness or neuromuscular problems (especially if related to myasthenia gravis)

Diagnostic Methods
The methods used to diagnose thymus diseases include:

  • Chest X-ray: Shows the size of the thymus and presence of masses.
  • Computed Tomography (CT) and Magnetic Resonance Imaging (MRI): Used for detailed imaging of the thymus.
  • Biopsy: A tissue sample may be taken to determine whether a mass is benign or malignant.
  • Blood Tests: Useful especially for evaluating accompanying diseases such as myasthenia gravis.

Treatment Options
Treatment for thymus diseases varies according to the type and extent of the disease.

Surgical Treatment
Surgery is the most common treatment for thymus diseases. The goal is to remove the entire mass in cases of thymus tumors or cysts. Surgical intervention is important to reduce symptoms and stop disease progression.

Medication
Medication may be used for immune system disorders related to thymus diseases, such as myasthenia gravis. Immunomodulatory drugs are administered.

Radiotherapy and Chemotherapy
Radiotherapy and chemotherapy may be applied in cases of thymus cancer or malignant thymomas. These treatments are used in addition to surgery or when surgery is not possible.

Thymus Disease Treatment at Healme Clinic
Healme Clinic offers comprehensive diagnostic and treatment services for thymus diseases with an experienced expert team and modern technological equipment. Personalized treatment plans, multidisciplinary approaches, and postoperative follow-up improve patients' quality of life.
Although rare, thymus diseases are important health issues. With early diagnosis and appropriate treatment, patients’ health and quality of life can be preserved. If you have any complaints or symptoms in the chest area, it is important to visit an experienced center for necessary examinations. Healme Clinic is here for you with its expert team specialized in thymus diseases.